Title : TDAG8 activation attenuates cerebral ischaemia-reperfusion injury via Akt signalling in rats.

Pub. Date : 2017 Jul

PMID : 28365474






1 Functional Relationships(s)
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1 Pretreatment with BTB09089 up-regulated TDAG8 and Bcl-2 expression and down-regulated cleaved caspase-3 expression, while the infarction volume was reduced, and neurological deficits were ameliorated 24 and 72h after MCAO. 3-((2,4-dichlorobenzyl)thio)-1,6-dimethyl-5,6-dihydro-1H-pyridazino(4,5-e)(1,3,4)thiadiazin-5-one caspase 3 Rattus norvegicus