Pub. Date : 2017
PMID : 28352264
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Indole-Induced Activities of beta-Lactamase and Efflux Pump Confer Ampicillin Resistance in Pseudomonas putida KT2440. | Ampicillin | class C beta-lactamase | Pseudomonas putida KT2440 |
| 2 | Transcriptome, mutant, and inhibitor studies have suggested that Amp resistance induced by indole can be attributed to increased gene expression of ttgAB encoding two genes of RND-type multidrug efflux operons and an ampC encoding beta-lactamase. | Ampicillin | class C beta-lactamase | Pseudomonas putida KT2440 |
| 3 | Expression, enzyme activities, and mutational analyses indicated that AmpC beta-lactamase is important for acquiring Amp resistance of P. putida in the presence of indole. | Ampicillin | class C beta-lactamase | Pseudomonas putida KT2440 |
| 4 | Our data indicates that indole reduces Amp-induced heterogeneity by promoting expression of TtgABC or MexAB-OprM efflux pumps and the indole-induced beta-lactamase in P. putida and P. aeruginosa. | Ampicillin | class C beta-lactamase | Pseudomonas putida KT2440 |