Title : ABCB1 and ABCG2 drug transporters are differentially expressed in non-small cell lung cancers (NSCLC) and expression is modified by cisplatin treatment via altered Wnt signaling.

Pub. Date : 2017 Mar 24

PMID : 28340578






1 Functional Relationships(s)
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1 In contrast, cisplatin, the frequently used adjuvant chemotherapeutic agent, activated beta-catenin dependent signaling that lead to up-regulation of both ABCB1 and ABCG2 transporter expression and activity. Cisplatin catenin beta 1 Homo sapiens