Title : Induction of G2M Arrest by Flavokawain A, a Kava Chalcone, Increases the Responsiveness of HER2-Overexpressing Breast Cancer Cells to Herceptin.

Pub. Date : 2017 Mar 14

PMID : 28335434






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 FKA induces G2M arrest in cell cycle progression of HER2-overexpressing breast cancer cell lines through inhibition of Cdc2 and Cdc25C phosphorylation and downregulation of expression of Myt1 and Wee1 leading to increased Cdc2 kinase activities. flavokawain A cyclin dependent kinase 1 Homo sapiens
2 FKA induces G2M arrest in cell cycle progression of HER2-overexpressing breast cancer cell lines through inhibition of Cdc2 and Cdc25C phosphorylation and downregulation of expression of Myt1 and Wee1 leading to increased Cdc2 kinase activities. flavokawain A cyclin dependent kinase 1 Homo sapiens