Pub. Date : 2017
PMID : 28334039
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We hypothesized the anti-inflammatory effects of L-Arg require active transport and metabolism by inducible nitric oxide synthase (iNOS) to generate nitric oxide (NO). | Arginine | nitric oxide synthase 2 | Homo sapiens |
| 2 | We hypothesized the anti-inflammatory effects of L-Arg require active transport and metabolism by inducible nitric oxide synthase (iNOS) to generate nitric oxide (NO). | Arginine | nitric oxide synthase 2 | Homo sapiens |
| 3 | CONCLUSION: The inhibitory effects of L-Arg on IL-1beta-mediated NF-kappaB-activation in Caco-2 cells involve L-Arg transport activity by CAT1, regulation of IL-1beta-mediated increases in NF-kappaB expression, changes in iNOS expression and NO production. | Arginine | nitric oxide synthase 2 | Homo sapiens |
| 4 | Our data suggest the inhibitory effects of L-Arg on NF-kappaB activation are mediated in part by iNOS since SNP preserves and NNA attenuates the effects of L-Arg on IL-1beta-mediated NF-kappaB-activation and expression. | Arginine | nitric oxide synthase 2 | Homo sapiens |
| 5 | Our data suggest the inhibitory effects of L-Arg on NF-kappaB activation are mediated in part by iNOS since SNP preserves and NNA attenuates the effects of L-Arg on IL-1beta-mediated NF-kappaB-activation and expression. | Arginine | nitric oxide synthase 2 | Homo sapiens |