Title : Polymorphism in XRCC1 gene modulates survival and clinical outcomes of advanced North Indian lung cancer patients treated with platinum-based doublet chemotherapy.

Pub. Date : 2017 Apr

PMID : 28332164






1 Functional Relationships(s)
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1 On stratification according to chemotherapy regimen administered; cisplatin/carboplatin + docetaxel was observed to increase survival for XRCC1 399 mutant genotype (AA) (HR 0.26, p = 0.05). Cisplatin X-ray repair cross complementing 1 Homo sapiens