Title : Doxorubicin induces cardiotoxicity through upregulation of death receptors mediated apoptosis in cardiomyocytes.

Pub. Date : 2017 Mar 16

PMID : 28300219






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We found that doxorubicin and related anthracycline agents (e.g., daunorubicin, idarubicin, and epirubicin) significantly upregulated the expression of death receptors (DRs) (TNFR1, Fas, DR4 and DR5) in iPS-derived cardiomyocytes at both protein and mRNA levels. Epirubicin TNF receptor superfamily member 1A Homo sapiens