Title : The α-cyclodextrin complex of the Moringa isothiocyanate suppresses lipopolysaccharide-induced inflammation in RAW 264.7 macrophage cells through Akt and p38 inhibition.

Pub. Date : 2017 Jun

PMID : 28289752






1 Functional Relationships(s)
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1 Our results showed that moringin + alpha-CD inhibits the production of inflammatory mediators in LPS-stimulated macrophages by down-regulation of pro-inflammatory cytokines (TNF-alpha and IL-1beta), by preventing IkappaB-alpha phosphorylation, translocation of the nuclear factor-kappaB (NF-kappaB), and also via the suppression of Akt and p38 phosphorylation. moringin tumor necrosis factor Mus musculus