Title : Ginsenoside Rg5 Inhibits Succinate-Associated Lipolysis in Adipose Tissue and Prevents Muscle Insulin Resistance.

Pub. Date : 2017

PMID : 28261091






2 Functional Relationships(s)
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1 Ginsenoside Rg5 treatment suppressed NLRP3 inflammasome activation, preserved PDE3B expression and then reduced cAMP accumulation, contributing to inhibition of lipolysis. Ginsenosides NLR family pyrin domain containing 3 Homo sapiens
2 These findings establish a previously unrecognized role of ginsenosides in the regulation of lipid and glucose homeostasis and suggest that adipose succinate-associated NLRP3 inflammasome activation might be targeted therapeutically to prevent lipolysis and insulin resistance. Ginsenosides NLR family pyrin domain containing 3 Homo sapiens