Title : Attenuation of prostaglandin E1‑induced osteoprotegerin synthesis in osteoblasts by normoxic HIF inducers.

Pub. Date : 2017 Apr

PMID : 28259984






5 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Previous evidence has indicated that HIF regulates angiogenesis-osteogenesis coupling in bone metabolism, and it has previously been reported that mimosine inhibits prostaglandin (PG)F2alpha-induced osteoprotegerin (OPG) synthesis without affecting interleukin-6 (IL-6) production in osteoblast-like MC3T3-E1 cells. Mimosine tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) Mus musculus
2 Previous evidence has indicated that HIF regulates angiogenesis-osteogenesis coupling in bone metabolism, and it has previously been reported that mimosine inhibits prostaglandin (PG)F2alpha-induced osteoprotegerin (OPG) synthesis without affecting interleukin-6 (IL-6) production in osteoblast-like MC3T3-E1 cells. Mimosine tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) Mus musculus
3 In the present study, the effects of mimosine on the PGE1-stimulated synthesis of OPG and IL-6 were investigated in osteoblast-like MC3T3-E1 cells. Mimosine tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) Mus musculus
4 Mimosine significantly reduced PGE1-induced release of OPG and OPG mRNA expression levels without affecting the release of IL-6. Mimosine tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) Mus musculus
5 Mimosine significantly reduced PGE1-induced release of OPG and OPG mRNA expression levels without affecting the release of IL-6. Mimosine tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) Mus musculus