Protein Name tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
Organism Mus musculus
Gene ID 18383
Gene Symbol

Tnfrsf11b

UniProt O08712 (TR11B_MOUSE), Q3UK97 (Q3UK97_MOUSE)
Relationships Total Number of functionally related compound(s) : 309
Total Number of Articles : 378
Description

tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)

Gene Summary

Acts upstream of or within extracellular matrix organization and negative regulation of odontogenesis of dentin-containing tooth. Located in extracellular matrix. Is expressed in several structures, including arterial system; bone; gut; lung; and placenta. Used to study osteoporosis. Human ortholog(s) of this gene implicated in Paget's disease of bone and osteoarthritis. Orthologous to human TNFRSF11B (TNF receptor superfamily member 11b). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • tumor necrosis factor receptor superfamily member 11B
  • osteoclastogenesis inhibitory factor
  • osteoprotegerin
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Properties