Title : TNF-α, IL-6 and IL-10 expressions, responsible for disparity in action of curcumin against cisplatin-induced nephrotoxicity in rats.

Pub. Date : 2017 Jul

PMID : 28258441






2 Functional Relationships(s)
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1 In addition, cisplatin showed a marked pro-inflammatory response as revealed by a significant increase in the tissue levels of TNF-alpha, IL-6, IL-8 and decrease in the IL-10 level. Cisplatin tumor necrosis factor Rattus norvegicus
2 Pre-treatment of curcumin reduced cisplatin-induced nephrotoxicity which was clearly evident from the reduced BUN, creatinine, TNF-alpha, IL-6 and IL-8 levels and increased albumin and IL-10 levels. Cisplatin tumor necrosis factor Rattus norvegicus