Pub. Date : 1987 Nov 13
PMID : 2825684
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Addition of the tumor promoter phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA), at concentrations which activate pituitary protein C kinase, to cultured pituitary cells resulted in up-regulation of GnRH receptors (155% at 4 h). | Tetradecanoylphorbol Acetate | gonadotropin releasing hormone 1 | Homo sapiens |
| 2 | Addition of the tumor promoter phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA), at concentrations which activate pituitary protein C kinase, to cultured pituitary cells resulted in up-regulation of GnRH receptors (155% at 4 h). | Tetradecanoylphorbol Acetate | gonadotropin releasing hormone 1 | Homo sapiens |
| 3 | The stimulatory effect of GnRH on [3H]inositol phosphates (Ins-P) production in myo-[2-3H]inositol prelabeled pituitary cells was not inhibited by prior treatment of the cells with TPA (10(-9)-10(-7) M). | Tetradecanoylphorbol Acetate | gonadotropin releasing hormone 1 | Homo sapiens |
| 4 | Higher concentrations of TPA (10(-6)-10(-5) M) inhibited the effect of GnRH on [3H]Ins-P production. | Tetradecanoylphorbol Acetate | gonadotropin releasing hormone 1 | Homo sapiens |