Pub. Date : 2017
PMID : 28255267
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | 17beta-estradiol Attenuates TNF-alpha-Induced Premature Senescence of Nucleus Pulposus Cells through Regulating the ROS/NF-kappaB Pathway. | Reactive Oxygen Species | tumor necrosis factor | Rattus norvegicus |
| 2 | Furthermore, E2 inhibited ROS generation and phospho-NF-kappaB/p65 expression in the TNF-alpha-treated NP cells. | Reactive Oxygen Species | tumor necrosis factor | Rattus norvegicus |
| 3 | CONCLUSION: The interaction between E2 and ER can attenuate TNF-alpha-induced premature senescence of rat NP cells through interfering with the ROS/NF-kappaB pathway. | Reactive Oxygen Species | tumor necrosis factor | Rattus norvegicus |