Title : Histamine-producing cell-stimulating activity. Interleukin 3 and granulocyte-macrophage colony-stimulating factor induce de novo synthesis of histidine decarboxylase in hemopoietic progenitor cells.

Pub. Date : 1987 Dec 1

PMID : 2824613






1 Functional Relationships(s)
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1 Histidine-free culture conditions or addition of alpha-fluoromethylhistidine, an irreversible inhibitor of histidine decarboxylase, completely abrogate this phenomenon, indicating that increased histamine levels result from an augmentation of the rate of its synthesis. alpha-fluoromethylhistidine histidine decarboxylase Mus musculus