Protein Name histidine decarboxylase
Organism Mus musculus
Gene ID 15186
Gene Symbol

Hdc

UniProt P23738 (DCHS_MOUSE)
Relationships Total Number of functionally related compound(s) : 196
Total Number of Articles : 305
Description

histidine decarboxylase

Gene Summary

Enables histidine decarboxylase activity. Acts upstream of or within L-histidine catabolic process and histamine biosynthetic process. Predicted to be located in dendrite and neuronal cell body. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and respiratory system. Used to study Gilles de la Tourette syndrome. Human ortholog(s) of this gene implicated in Gilles de la Tourette syndrome; asthma; and rhinitis. Orthologous to human HDC (histidine decarboxylase). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • histidine decarboxylase
  • L-histidine decarboxylase
  • Hdc-a
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Properties