Title : Estimation of the Contribution of CYP2C8 and CYP3A4 in Repaglinide Metabolism by Human Liver Microsomes Under Various Buffer Conditions.

Pub. Date : 2017 Sep

PMID : 28238899






1 Functional Relationships(s)
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1 Montelukast and ketoconazole showed a potent and concentration-dependent inhibition of CYP2C8-mediated paclitaxel 6alpha-hydroxylation and CYP3A4-mediated triazolam alpha-hydroxylation, respectively, without dependence on the buffer condition. montelukast cytochrome P450 family 2 subfamily C member 8 Homo sapiens