Title : Dexmedetomidine protects against cisplatin-induced acute kidney injury in mice through regulating apoptosis and inflammation.

Pub. Date : 2017 May

PMID : 28224201






1 Functional Relationships(s)
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1 DEX suppressed the infiltration of macrophages and T cells into the kidneys following cisplatin treatment, which was involved in the inhibition of NF-kappaB activation and decreased expression of TNF-alpha, IL-1beta, IL-6, and MCP-1. Cisplatin tumor necrosis factor Mus musculus