Pub. Date : 1987 Nov 15
PMID : 2822236
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Influence of D-glucose upon the respiratory and secretory response of insulin-producing tumor cells to 2-aminobicyclo[2,2,1]heptane-2-carboxylic acid. | 2-aminobicyclo(2,2,1)heptane-2-carboxylic acid | insulin | Homo sapiens |
| 2 | In insulin-producing cells of the RINm5F line, the nonmetabolized analogue of L-leucine, 2-aminobicyclo[2,2,1]heptane-2-carboxylic acid decreases O2 consumption, lowers ATP content, and inhibits insulin release despite stimulation of both NH4 production and 14CO2 output from cells prelabeled with L-[U-14C]glutamine. | 2-aminobicyclo(2,2,1)heptane-2-carboxylic acid | insulin | Homo sapiens |
| 3 | In insulin-producing cells of the RINm5F line, the nonmetabolized analogue of L-leucine, 2-aminobicyclo[2,2,1]heptane-2-carboxylic acid decreases O2 consumption, lowers ATP content, and inhibits insulin release despite stimulation of both NH4 production and 14CO2 output from cells prelabeled with L-[U-14C]glutamine. | 2-aminobicyclo(2,2,1)heptane-2-carboxylic acid | insulin | Homo sapiens |
| 4 | The metabolic and secretory effects of 2-aminobicyclo[2,2,1]heptane-2-carboxylic acid are opposed to those of D-glucose, which increases respiration, ATP content, and insulin release, while lowering NH4+ production and 14CO2 output from the prelabeled cells. | 2-aminobicyclo(2,2,1)heptane-2-carboxylic acid | insulin | Homo sapiens |