Title : Discovery and characterization of novel CYP1B1 inhibitors based on heterocyclic chalcones: Overcoming cisplatin resistance in CYP1B1-overexpressing lines.

Pub. Date : 2017 Mar 31

PMID : 28222316






1 Functional Relationships(s)
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1 The structure of alpha-napthoflavone (ANF), a potent inhibitor of CYP1A1 and CYP1B1, mimics the structure of chalcones. Chalcones cytochrome P450 family 1 subfamily A member 1 Homo sapiens