Title : Phorbol ester induces interleukin-2 receptor on the cell surface of precursor thymocyte leukemia with no rearrangement of T cell receptor beta and gamma genes.

Pub. Date : 1987 Nov

PMID : 2822168






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Stimulation of these pre-T-ALL cells with 12-0-tetradecanoylphorbol-13-acetate (TPA) induced only CD25 (Tac) antigen but no other T cell antigens. Tetradecanoylphorbol Acetate interleukin 2 receptor subunit alpha Homo sapiens
2 TPA induced the differentiation of the more mature pre-T-ALL cells of this case in vitro, and not only CD25 (Tac) antigen but also CD4 and CD8 antigens appeared on the cell surface. Tetradecanoylphorbol Acetate interleukin 2 receptor subunit alpha Homo sapiens