Title : Vitamin D signaling and melanoma: role of vitamin D and its receptors in melanoma progression and management.

Pub. Date : 2017 Jun

PMID : 28218743






1 Functional Relationships(s)
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Protein Name
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1 Vitamin D is activated through hydroxylation by 25-hydroxylases (CYP2R1 or CYP27A1) and 1alpha-hydroxylase (CYP27B1) to produce 1,25(OH)2D3, or through the action of CYP11A1 to produce mono-di- and trihydroxy-D3 products that can be further modified by CYP27B1, CYP27A1, and CYP24A1. Cholecalciferol cytochrome P450 family 2 subfamily R member 1 Homo sapiens