Title : Enhancement of antigen-specific CD4+ and CD8+ T cell responses using a self-assembled biologic nanolipoprotein particle vaccine.

Pub. Date : 2017 Mar 13

PMID : 28214044






1 Functional Relationships(s)
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1 Delivery of OVA with the TLR4 agonist monophosphoryl lipid A (MPLA) in the context of NLPs significantly enhanced the activation of both CD4+ and CD8+ T cells in vitro compared to co-administration of free OVA and MPLA. monophosphoryl toll-like receptor 4 Mus musculus