Pub. Date : 2017 Mar 25
PMID : 28202417
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Triptolide treatment attenuated TAC-induced myocardial remodeling, improved cardiac diastolic and systolic function, inhibited the NLRP3 inflammasome and downstream inflammatory mediators (IL-1beta, IL-18, MCP-1, VCAM-1), activated the profibrotic TGF-beta1 pathway, and suppressed macrophage infiltration in a dose-dependent manner. | triptolide | interleukin 18 | Mus musculus |