Pub. Date : 2020 Apr
PMID : 28195449
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | BACKGROUND: We observed the effects of resveratrol on the expression of molecules involved in the mTOR signaling pathway in pathological scar fibroblasts, including PI3K, Akt and mTOR. | Resveratrol | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | After being treated with different concentrations of resveratrol, the expression of PI3K, Akt and mTOR mRNA and protein were detected by RT-PCR and Western Blot respectively. | Resveratrol | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | CONCLUSIONS: The mechanism of resveratrol in the inhibition of the proliferation of pathological scar fibroblasts may be related to its down-regulation in the expression of Akt and mTOR, which are the key molecules of mTOR signaling pathway. | Resveratrol | AKT serine/threonine kinase 1 | Homo sapiens |