Pub. Date : 2020 Apr
PMID : 28195449
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effects of resveratrol on the expression of molecules related to the mTOR signaling pathway in pathological scar fibroblasts. | Resveratrol | mechanistic target of rapamycin kinase | Homo sapiens |
| 2 | BACKGROUND: We observed the effects of resveratrol on the expression of molecules involved in the mTOR signaling pathway in pathological scar fibroblasts, including PI3K, Akt and mTOR. | Resveratrol | mechanistic target of rapamycin kinase | Homo sapiens |
| 3 | BACKGROUND: We observed the effects of resveratrol on the expression of molecules involved in the mTOR signaling pathway in pathological scar fibroblasts, including PI3K, Akt and mTOR. | Resveratrol | mechanistic target of rapamycin kinase | Homo sapiens |
| 4 | After being treated with different concentrations of resveratrol, the expression of PI3K, Akt and mTOR mRNA and protein were detected by RT-PCR and Western Blot respectively. | Resveratrol | mechanistic target of rapamycin kinase | Homo sapiens |
| 5 | CONCLUSIONS: The mechanism of resveratrol in the inhibition of the proliferation of pathological scar fibroblasts may be related to its down-regulation in the expression of Akt and mTOR, which are the key molecules of mTOR signaling pathway. | Resveratrol | mechanistic target of rapamycin kinase | Homo sapiens |
| 6 | CONCLUSIONS: The mechanism of resveratrol in the inhibition of the proliferation of pathological scar fibroblasts may be related to its down-regulation in the expression of Akt and mTOR, which are the key molecules of mTOR signaling pathway. | Resveratrol | mechanistic target of rapamycin kinase | Homo sapiens |