Pub. Date : 2017 Apr
PMID : 28186503
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We found that following 12-O-tetradecanoyl-phorbol-13-acetate (TPA) topical treatment, DLX3 expression is significantly upregulated in the epidermis and keratinocytes from mice overexpressing PKCalpha by transgenic targeting (K5-PKCalpha), resulting in cell cycle block and terminal differentiation. | Tetradecanoylphorbol Acetate | distal-less homeobox 3 | Mus musculus |
| 2 | We found that following 12-O-tetradecanoyl-phorbol-13-acetate (TPA) topical treatment, DLX3 expression is significantly upregulated in the epidermis and keratinocytes from mice overexpressing PKCalpha by transgenic targeting (K5-PKCalpha), resulting in cell cycle block and terminal differentiation. | Tetradecanoylphorbol Acetate | distal-less homeobox 3 | Mus musculus |
| 3 | Of particular significance, transcriptional activation of epidermal barrier, antimicrobial peptide and cytokine genes is significantly increased in DLX3cKO skin and further increased by TPA-dependent PKC activation. | Tetradecanoylphorbol Acetate | distal-less homeobox 3 | Mus musculus |