Protein Name distal-less homeobox 3
Organism Mus musculus
Gene ID 13393
Gene Symbol

Dlx3

UniProt Q64205 (DLX3_MOUSE), Q78ZZ8 (Q78ZZ8_MOUSE)
Relationships Total Number of functionally related compound(s) : 11
Total Number of Articles : 12
Description

distal-less homeobox 3

Gene Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and chromatin binding activity. Acts upstream of or within several processes, including odontoblast differentiation; odontogenesis of dentin-containing tooth; and placenta development. Located in nucleus. Is expressed in several structures, including brain; branchial arch; genitourinary system; jaw; and sensory organ. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 4 and trichodontoosseous syndrome. Orthologous to human DLX3 (distal-less homeobox 3). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • homeobox protein DLX-3
  • DII C
  • Dlx-3
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Properties