Title : SIRT2 inhibition modulate glutamate and serotonin systems in the prefrontal cortex and induces antidepressant-like action.

Pub. Date : 2017 May 1

PMID : 28185898






2 Functional Relationships(s)
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1 SIRT2 inhibition modulate glutamate and serotonin systems in the prefrontal cortex and induces antidepressant-like action. Serotonin sirtuin 2 Mus musculus
2 These results suggest that Sirt2 inhibition induce antidepressant-like action and this effect could be mediated by modulation of glutamate and serotonin system in the PFC. Serotonin sirtuin 2 Mus musculus