Title : Reduced stress granule formation and cell death in fibroblasts with the A382T mutation of TARDBP gene: evidence for loss of TDP-43 nuclear function.

Pub. Date : 2016 Oct 15

PMID : 28172957






1 Functional Relationships(s)
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1 Under stress conditions induced by sodium arsenite, we found that in human fibroblasts TDP-43 did not translocate to the SGs but instead contributed to the SG formation through a regulatory effect on the G3BP1 core protein. sodium arsenite TAR DNA binding protein Homo sapiens