Pub. Date : 2017 Mar 11
PMID : 28161641
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Neferine reduces cisplatin-induced nephrotoxicity by enhancing autophagy via the AMPK/mTOR signaling pathway. | neferine | protein kinase AMP-activated catalytic subunit alpha 1 | Homo sapiens |
| 2 | Furthermore, neferine pretreatment activated the AMPK/mTOR pathway; however, pharmacological inhibition of AMPK abolished neferine-mediated autophagy and nephroprotection against cisplatin-induced apoptosis. | neferine | protein kinase AMP-activated catalytic subunit alpha 1 | Homo sapiens |
| 3 | Furthermore, neferine pretreatment activated the AMPK/mTOR pathway; however, pharmacological inhibition of AMPK abolished neferine-mediated autophagy and nephroprotection against cisplatin-induced apoptosis. | neferine | protein kinase AMP-activated catalytic subunit alpha 1 | Homo sapiens |