Pub. Date : 2016
PMID : 28149280
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The MEK-Inhibitor Selumetinib Attenuates Tumor Growth and Reduces IL-6 Expression but Does Not Protect against Muscle Wasting in Lewis Lung Cancer Cachexia. | AZD 6244 | interleukin 6 | Homo sapiens |
2 | Moreover, Selumetinib has also been shown to inhibit the production of IL-6. | AZD 6244 | interleukin 6 | Homo sapiens |
3 | Treatment with Selumetinib reduced tumor mass and reduced circulating and tumor IL-6; however MEK inhibition did not preserve muscle mass. | AZD 6244 | interleukin 6 | Homo sapiens |