Pub. Date : 2017 Sep
PMID : 28135009
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | ATP-binding cassette subfamily B member 1 1236C/T polymorphism significantly affects the therapeutic outcome of tacrolimus in patients with refractory ulcerative colitis. | Tacrolimus | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | Both cytochrome P-450 3A5 (CYP3A5) and ATP-binding cassette subfamily B member 1 (ABCB1) associated with tacrolimus metabolism are known to have several genetic polymorphisms. | Tacrolimus | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | Both cytochrome P-450 3A5 (CYP3A5) and ATP-binding cassette subfamily B member 1 (ABCB1) associated with tacrolimus metabolism are known to have several genetic polymorphisms. | Tacrolimus | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 4 | We aimed to investigate the influence of both CYP3A5 and ABCB1 polymorphisms on the efficacy of tacrolimus in ulcerative colitis treatment under the tight dose-adjusting strategy. | Tacrolimus | ATP binding cassette subfamily B member 1 | Homo sapiens |