Pub. Date : 2016
PMID : 28119604
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Most importantly, recently identified GTP-binding inhibitors, 68 and FX2149, can reduce LRRK2 GTP-binding activity and attenuates R1441C-induced mitochondrial and lysosomal transport impairments. | Guanosine Triphosphate | leucine rich repeat kinase 2 | Homo sapiens |
| 2 | Most importantly, recently identified GTP-binding inhibitors, 68 and FX2149, can reduce LRRK2 GTP-binding activity and attenuates R1441C-induced mitochondrial and lysosomal transport impairments. | Guanosine Triphosphate | leucine rich repeat kinase 2 | Homo sapiens |
| 3 | This is the first report to show that LRRK2 GTP-binding activity plays a critical role during neurite transport, suggesting inhibition of LRRK2 GTP-binding could be a potential novel strategy for PD intervention. | Guanosine Triphosphate | leucine rich repeat kinase 2 | Homo sapiens |
| 4 | This is the first report to show that LRRK2 GTP-binding activity plays a critical role during neurite transport, suggesting inhibition of LRRK2 GTP-binding could be a potential novel strategy for PD intervention. | Guanosine Triphosphate | leucine rich repeat kinase 2 | Homo sapiens |
| 5 | This is the first report to show that LRRK2 GTP-binding activity plays a critical role during neurite transport, suggesting inhibition of LRRK2 GTP-binding could be a potential novel strategy for PD intervention. | Guanosine Triphosphate | leucine rich repeat kinase 2 | Homo sapiens |
| 6 | This is the first report to show that LRRK2 GTP-binding activity plays a critical role during neurite transport, suggesting inhibition of LRRK2 GTP-binding could be a potential novel strategy for PD intervention. | Guanosine Triphosphate | leucine rich repeat kinase 2 | Homo sapiens |