Title : Pharmacological investigation on the anti-oxidant and anti-inflammatory activity of N-acetylcysteine in an ex vivo model of COPD exacerbation.

Pub. Date : 2017 Jan 24

PMID : 28118826






1 Functional Relationships(s)
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1 Concentrations of NAC >=300 muM inhibited the inflammatory response (release of IL-1beta, IL-8, and TNF-alpha) of human airways induced by the overnight stimulation with LPS, whereas lower concentrations of NAC (>=1 muM) were sufficient to reduce the release of IL-6 elicited by LPS. Acetylcysteine interleukin 6 Homo sapiens