Title : Apelin protects against NMDA-induced retinal neuronal death via an APJ receptor by activating Akt and ERK1/2, and suppressing TNF-α expression in mice.

Pub. Date : 2017 Jan

PMID : 28087150






3 Functional Relationships(s)
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1 Apelin protects against NMDA-induced retinal neuronal death via an APJ receptor by activating Akt and ERK1/2, and suppressing TNF-alpha expression in mice. N-Methylaspartate tumor necrosis factor Mus musculus
2 Additionally, an intravitreal injection of tumor necrosis factor-alpha (TNF-alpha) neutralizing antibody prevented NMDA-induced retinal neuronal cell death, and exogenous and endogenous apelin suppressed NMDA-induced upregulation of TNF-alpha in the retina. N-Methylaspartate tumor necrosis factor Mus musculus
3 Additionally, an intravitreal injection of tumor necrosis factor-alpha (TNF-alpha) neutralizing antibody prevented NMDA-induced retinal neuronal cell death, and exogenous and endogenous apelin suppressed NMDA-induced upregulation of TNF-alpha in the retina. N-Methylaspartate tumor necrosis factor Mus musculus