Title : Sphingosine-1-phosphate signalling-a key player in the pathogenesis of Angiotensin II-induced hypertension.

Pub. Date : 2017 Feb

PMID : 28082452






1 Functional Relationships(s)
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1 T-cell egress from lymph nodes was found to be a critical initial step for the onset of hypertension as fingolimod, a S1P-receptor agonist sequestering lymphocytes in the lymph nodes and inducing lymphopenia, blunted BP responses to AngII. Fingolimod Hydrochloride angiotensinogen (serpin peptidase inhibitor, clade A, member 8) Mus musculus