Pub. Date : 2017 Feb
PMID : 28065786
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Cisplatin-induced necroptosis in TNFalpha dependent and independent pathways. | Cisplatin | tumor necrosis factor | Mus musculus |
2 | Moreover, we demonstrate that the mitochondrial permeability transition pore opening (mPTP) opening and reactive oxygen species (ROS) generation is a critical downstream event of the formation of necrosome in cisplatin-induced necroptosis, which is TNFalpha independent. | Cisplatin | tumor necrosis factor | Mus musculus |
3 | Both deletion of CypD and TNFalpha completely blocked cisplatin-induced cell death, suggesting that cisplatin could induce necroptosis through TNFalpha dependent and independent pathway. | Cisplatin | tumor necrosis factor | Mus musculus |
4 | Both deletion of CypD and TNFalpha completely blocked cisplatin-induced cell death, suggesting that cisplatin could induce necroptosis through TNFalpha dependent and independent pathway. | Cisplatin | tumor necrosis factor | Mus musculus |
5 | Both deletion of CypD and TNFalpha completely blocked cisplatin-induced cell death, suggesting that cisplatin could induce necroptosis through TNFalpha dependent and independent pathway. | Cisplatin | tumor necrosis factor | Mus musculus |
6 | Both deletion of CypD and TNFalpha completely blocked cisplatin-induced cell death, suggesting that cisplatin could induce necroptosis through TNFalpha dependent and independent pathway. | Cisplatin | tumor necrosis factor | Mus musculus |