Title : Pharmacokinetics and Pharmacogenetics of Carbamazepine in Children.

Pub. Date : 2017 Oct

PMID : 28064419






2 Functional Relationships(s)
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1 The current evidence on the importance of pharmacogenetics for carbamazepine efficacy and safety in children supports the association of PXR*1B, HNF4a rs2071197, CYP1A2*1F, ABCC2 1249G>A, and PRRT2 c.649dupC with either pharmacokinetics or pharmacodynamics of carbamazepine. Carbamazepine ATP binding cassette subfamily C member 2 Homo sapiens
2 The current evidence on the importance of pharmacogenetics for carbamazepine efficacy and safety in children supports the association of PXR*1B, HNF4a rs2071197, CYP1A2*1F, ABCC2 1249G>A, and PRRT2 c.649dupC with either pharmacokinetics or pharmacodynamics of carbamazepine. Carbamazepine ATP binding cassette subfamily C member 2 Homo sapiens