Pub. Date : 2017
PMID : 28053596
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Celecoxib enhances anticancer effect of cisplatin and induces anoikis in osteosarcoma via PI3K/Akt pathway. | Celecoxib | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | In our study, we have reported that celecoxib, a cyclooxygenase-2 inhibitor, induces apoptosis in human osteosarcoma cell line MG-63 via down-regulation of PI3K/Akt. | Celecoxib | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | CONCLUSION: Therefore, celecoxib enhances anticancer effect of cisplatin and induces anoikis in osteosarcoma, which may be PI3K/Akt-dependent, and MDR and beta-catenin-related. | Celecoxib | AKT serine/threonine kinase 1 | Homo sapiens |