Title : Celecoxib enhances anticancer effect of cisplatin and induces anoikis in osteosarcoma via PI3K/Akt pathway.

Pub. Date : 2017

PMID : 28053596






1 Functional Relationships(s)
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1 RESULTS: MDR1, MRP1, BCRP and Trkb, E-cadherin, beta-catenin were significantly downregulated in cells treated with the combination of celecoxib and cisplatin, and decreased beta-catenin level was found in cells with wortmannin, a specific PI3K inhibitor. Cisplatin ATP binding cassette subfamily B member 1 Homo sapiens