Title : Donor CYP3A5 genotype influences tacrolimus disposition on the first day after paediatric liver transplantation.

Pub. Date : 2017 Jun

PMID : 28044353






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1 METHODS: The contribution of the CYP3A4/5 genotype in paediatric liver transplant recipients and donors to the tacrolimus blood trough concentrations (C0 ) and the tacrolimus concentration/weight-adjusted dose ratio on day 1 was evaluated in 67 liver-transplanted children: 33 boys and 34 girls, mean age 4.5 years. Tacrolimus cytochrome P450 family 3 subfamily A member 4 Homo sapiens