Title : Role of prostaglandins in tumour necrosis factor induced weight loss.

Pub. Date : 1989 Jul

PMID : 2803915






2 Functional Relationships(s)
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1 A single injection of TNF-alpha caused an enhanced production of PGE2 by spleen cells from treated animals, that was significant within 1 h of treatment, and persisted until at least 6 h. These results suggest that the anorectic effect of TNF-alpha may be mediated by a prostaglandin intermediate. Prostaglandins tumor necrosis factor Mus musculus
2 A single injection of TNF-alpha caused an enhanced production of PGE2 by spleen cells from treated animals, that was significant within 1 h of treatment, and persisted until at least 6 h. These results suggest that the anorectic effect of TNF-alpha may be mediated by a prostaglandin intermediate. Prostaglandins tumor necrosis factor Mus musculus