Title : Ginsenoside Rb2 enhances the anti-inflammatory effect of ω-3 fatty acid in LPS-stimulated RAW264.7 macrophages by upregulating GPR120 expression.

Pub. Date : 2017 Feb

PMID : 28017961






3 Functional Relationships(s)
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1 Treatment with a omega-3 fatty acid alpha-linolenic acid (ALA, 50 mumol/L) produced moderate reduction in LPS-stimulated inflammatory cytokines and NO production (TNF-alpha and IL-6 were decreased by 46% and 42%, respectively). alpha-Linolenic Acid interleukin 6 Mus musculus
2 Treatment with a omega-3 fatty acid alpha-linolenic acid (ALA, 50 mumol/L) produced moderate reduction in LPS-stimulated inflammatory cytokines and NO production (TNF-alpha and IL-6 were decreased by 46% and 42%, respectively). alpha-Linolenic Acid interleukin 6 Mus musculus
3 Pre-incubation with Rb2 (1 or 10 mumol/L) for 12 h before ALA treatment dramatically amplified the inhibitory effects of ALA (TNF-alpha and IL-6 were decreased by 74% and 86%, respectively). alpha-Linolenic Acid interleukin 6 Mus musculus