Pub. Date : 2017 Feb
PMID : 28011380
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Propofol enhances the cisplatin-induced apoptosis on cervical cancer cells via EGFR/JAK2/STAT3 pathway. | Cisplatin | epidermal growth factor receptor | Homo sapiens |
| 2 | In genetic level, propofol could enhance the anti-tumor effect of cisplatin through EGFR/JAK2/STAT3 pathway. | Cisplatin | epidermal growth factor receptor | Homo sapiens |
| 3 | Further studies indicated that overexpression of EGFR and STAT3 is related to poor prognoses in cervical cancer patients, which contributed to confirm the clinical role of combined application of propofol and cisplatin. | Cisplatin | epidermal growth factor receptor | Homo sapiens |
| 4 | CONCLUSION: Propofol enhances the cisplatin-induced cell apoptosis cervical cancer cells via EGFR/JAK2/STAT3 pathway and may be developed as a potential therapeutic agent to treat cervical cancer. | Cisplatin | epidermal growth factor receptor | Homo sapiens |