Title : Inflammation and exercise: Inhibition of monocytic intracellular TNF production by acute exercise via β2-adrenergic activation.

Pub. Date : 2017 Mar

PMID : 28011264






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1 This inhibitory response in TNF production by exercise was mirrored by beta-AR agonists in an agonist-specific and dose-dependent manner in vitro: similar isoproterenol (EC50=2.1-4.7x10-10M) and epinephrine (EC50=4.4-10x10-10M) potency and higher norepinephrine concentrations (EC50=2.6-4.3x10-8M) needed for the effects. Isoproterenol tumor necrosis factor Homo sapiens