Title : Changes in Serum Concentrations of Fibroblast Growth Factor 23 and Soluble Klotho in Hemodialysis Patients after Total Parathyroidectomy.

Pub. Date : 2016

PMID : 27999806






7 Functional Relationships(s)
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1 We examined the changes in circulating fibroblast growth factor 23 (FGF23) and Klotho concentrations in hemodialysis patients after parathyroidectomy (PTX). ptx fibroblast growth factor 23 Homo sapiens
2 Serum FGF23 and alpha-Klotho concentrations were elevated on days 5 and 90 after PTX compared to baseline (p > 0.05). ptx fibroblast growth factor 23 Homo sapiens
3 Serum FGF23 concentrations negatively correlated with serum calcium concentrations pre-PTX (Beta -0.31; R2 0.0949; p = 0.040), day 5 post-PTX (Beta -0.31; R2 0.0982; p = 0.036), and day 90 post-PTX (Beta -0.39; R2 0.1528; p = 0.008). ptx fibroblast growth factor 23 Homo sapiens
4 Serum FGF23 concentrations negatively correlated with serum calcium concentrations pre-PTX (Beta -0.31; R2 0.0949; p = 0.040), day 5 post-PTX (Beta -0.31; R2 0.0982; p = 0.036), and day 90 post-PTX (Beta -0.39; R2 0.1528; p = 0.008). ptx fibroblast growth factor 23 Homo sapiens
5 Serum FGF23 concentrations negatively correlated with serum calcium concentrations pre-PTX (Beta -0.31; R2 0.0949; p = 0.040), day 5 post-PTX (Beta -0.31; R2 0.0982; p = 0.036), and day 90 post-PTX (Beta -0.39; R2 0.1528; p = 0.008). ptx fibroblast growth factor 23 Homo sapiens
6 Serum FGF23 concentrations pre-PTX and at days 5 and 90 after PTX were inversely related to serum calcium concentrations. ptx fibroblast growth factor 23 Homo sapiens
7 Serum FGF23 concentrations pre-PTX and at days 5 and 90 after PTX were inversely related to serum calcium concentrations. ptx fibroblast growth factor 23 Homo sapiens