Protein Name fibroblast growth factor 23
Organism Homo sapiens
Gene ID 8074
Gene Symbol


UniProt Q9GZV9 (FGF23_HUMAN)
Relationships Total Number of functionally related compound(s) : 318
Total Number of Articles : 1461

fibroblast growth factor 23

Gene Summary

This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC). [provided by RefSeq, Feb 2013]

  • fibroblast growth factor 23
  • phosphatonin
  • tumor-derived hypophosphatemia inducing factor
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