| Protein Name | fibroblast growth factor 23 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 8074 |
| Gene Symbol | FGF23 |
| UniProt | Q9GZV9 (FGF23_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
318
Total Number of Articles : 1461 |
Description |
fibroblast growth factor 23 |
| Gene Summary |
This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC). [provided by RefSeq, Feb 2013] |
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