Title : LY3009120, a panRAF inhibitor, has significant anti-tumor activity in BRAF and KRAS mutant preclinical models of colorectal cancer.

Pub. Date : 2017 Feb 7

PMID : 27999210






1 Functional Relationships(s)
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1 Examination of potential resistance to LY3009120 demonstrated RAF-independent ERK and AKT activation in the KRASmut CRC cell line HCT 116. LY3009120 mitogen-activated protein kinase 1 Homo sapiens