Title : Growth Differentiation Factor 15 as a Novel Biomarker for Metformin.

Pub. Date : 2017 Feb

PMID : 27974345






8 Functional Relationships(s)
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1 Growth Differentiation Factor 15 as a Novel Biomarker for Metformin. Metformin growth differentiation factor 15 Homo sapiens
2 RESULTS: Growth differentiation factor 15 (GDF15) was strongly linked to metformin, such that the odds of metformin use per SD increase in level varied from 3.73 (95% CI 3.40, 4.09) to 3.94 (95% CI 3.59, 4.33) depending on the other included variables. Metformin growth differentiation factor 15 Homo sapiens
3 RESULTS: Growth differentiation factor 15 (GDF15) was strongly linked to metformin, such that the odds of metformin use per SD increase in level varied from 3.73 (95% CI 3.40, 4.09) to 3.94 (95% CI 3.59, 4.33) depending on the other included variables. Metformin growth differentiation factor 15 Homo sapiens
4 RESULTS: Growth differentiation factor 15 (GDF15) was strongly linked to metformin, such that the odds of metformin use per SD increase in level varied from 3.73 (95% CI 3.40, 4.09) to 3.94 (95% CI 3.59, 4.33) depending on the other included variables. Metformin growth differentiation factor 15 Homo sapiens
5 RESULTS: Growth differentiation factor 15 (GDF15) was strongly linked to metformin, such that the odds of metformin use per SD increase in level varied from 3.73 (95% CI 3.40, 4.09) to 3.94 (95% CI 3.59, 4.33) depending on the other included variables. Metformin growth differentiation factor 15 Homo sapiens
6 A 1.64 ng/mL higher GDF15 level predicted a 188-mg higher metformin dose (P < 0.0001). Metformin growth differentiation factor 15 Homo sapiens
7 CONCLUSIONS: GDF15 levels are a biomarker for the use of metformin in people with dysglycemia, and its concentration reflects the dose of metformin. Metformin growth differentiation factor 15 Homo sapiens
8 CONCLUSIONS: GDF15 levels are a biomarker for the use of metformin in people with dysglycemia, and its concentration reflects the dose of metformin. Metformin growth differentiation factor 15 Homo sapiens